|
KMID : 0372919890100030237
|
|
Journal of Biomedical Engineering Research
1989 Volume.10 No. 3 p.237 ~ p.241
|
|
|
Synthesis and Physical Properties of Biocompatible and Biodegradable Polypeptide Copolymers(II)
|
|
|
|
|
Abstract
|
|
|
|
The physical properties and drug release behaviours of polyethylene glycol grafted poly Y- benzyl L- glutamate (PEG- g- PBLG) , polyethylene glycol crosslinked poly Y-benzyl L- glutamate(PEG- c- PBLG), and PBLG homopolymer are compared. PBLG containing PEG segements showed higher wettability and larger enlongation than PBLG homoplymer, but lower elastic modulus. The release rate of rhodamine is strongly influenced by the wettability of the polymer. Rhodamine is more rapidly released from PEG- c- PBLG membrane having a larger water contact angle than from other polymer having a lower water contact angle. The surfaces of PBLG derivative membranes are modified by substitution reaction using hydroxyalkylamine. The resulting polymer membranes showed hider wettability and swelling ratio than virgin membranes.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|